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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18515 | Palbociclib-propargyl | PROTAC CDK6 ligand 1 | Others |
Palbociclib-propargyl, a PROTAC ligand targeting the protein CDK6, connects to the CRBN ligand through a PEG linker to form PROTAC CP-10. CP-10 exhibits a potent DC50 value of 2.1 nM against CDK6[1]. | |||
T17904 | Pomalidomide-PEG1-C2-N3 | E3 ligase Ligand-Linker Conjugates 50,Cereblon Ligand-Linker Conjugates 13 | Others |
Pomalidomide-PEG1-C2-N3 is a compound that has been synthesized as a conjugate of an E3 ligase ligand-linker. This compound incorporates the cereblon ligand based on Pomalidomide and a 1-unit PEG linker, which are common... |